7epw

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Crystal structure of monooxygenase Tet(X4) with tigecyclineCrystal structure of monooxygenase Tet(X4) with tigecycline

Structural highlights

7epw is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A3T0V9Y5_ECOLX] An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.[HAMAP-Rule:MF_00845]

7epw, resolution 2.23Å

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OCA