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STRUCTURE OF SCORPION NEUROTOXIN BMK M8STRUCTURE OF SCORPION NEUROTOXIN BMK M8
Structural highlights
FunctionSCX8_MESMA Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This acidic toxin has a weak toxicity and is active against mammals. Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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