Sculpting protein conformations

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This page is under development starting February 29, 2020. Please come back later to see it more fully developed.

Planned contents include PyMOL, Samson, and (now defunct) Sculpt. These programs enable protein conformations to be "sculpted" by dragging with the mouse.


Sometimes it is instructive to change the conformation of a protein model. Typically this means "sculpting" an experimentally-determined (empirical) model into a hypothetical conformation with some functional significance. There are software packages that enable this to be done using the mouse to drag portions of the original model into desired conformations.

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ReferencesReferences

  1. Surles MC, Richardson JS, Richardson DC, Brooks FP Jr. Sculpting proteins interactively: continual energy minimization embedded in a graphical modeling system. Protein Sci. 1994 Feb;3(2):198-210. PMID:8003957

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Eric Martz