6cl1

Caspase-7 in complex with Ac-DW3-KECaspase-7 in complex with Ac-DW3-KE

Structural highlights 6cl1 is a 6 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NonStd Res: , , Gene: CASP7, MCH3 (HUMAN) Activity: Caspase-7, with EC number 3.4.22.60 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. See Also Caspase 3D structures

spinqualitylabelsall models 6cl1, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image