6ivu

Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellumSolution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum

Structural highlights 6ivu is a 2 chain structure with sequence from Cloth. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 6ivs Gene: Cthe_0059 (CLOTH), sigI1, Cthe_0058 (CLOTH) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [RSGI1_CLOTH] Anti-sigma factor for SigI1. Negatively regulates SigI1 activity through direct interaction (PubMed:20937888). Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable). [SIGI1_CLOTH] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism. SigI1 promotes transcription from sigI1 and celS promoters (PubMed:20937888).[HAMAP-Rule:MF_02064]

spinqualitylabelsall models 6ivu, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image