Proteopedia

Ragulator complex

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The ragulator complex (Lamtor) is a pentamer which recruits mTORC1 in the rapamycin (mTOR) signal-transduction pathway and activates it[1].

Function

Disease

Relevance

Structural highlights

Caption for this structure

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ReferencesReferences

  1. ↑ Mu Z, Wang L, Deng W, Wang J, Wu G. Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane. Cell Discov. 2017 Dec 26;3:17049. doi: 10.1038/celldisc.2017.49. eCollection, 2017. PMID:29285400 doi:http://dx.doi.org/10.1038/celldisc.2017.49

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Michal Harel, Wayne Decatur
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