6mgp

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Structure of human 4-1BB / 4-1BBL complexStructure of human 4-1BB / 4-1BBL complex

Structural highlights

6mgp is a 6 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TNFL9_HUMAN] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. [TNR9_HUMAN] Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

6mgp, resolution 2.13Å

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OCA