Structure of human mitochondrial trifunctional protein, octamerStructure of human mitochondrial trifunctional protein, octamer

Structural highlights

5zrv is a 8 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Acetyl-CoA C-acyltransferase, with EC number 2.3.1.16
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

[ECHA_HUMAN] Mitochondrial trifunctional protein deficiency;Acute fatty liver of pregnancy;Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. [ECHB_HUMAN] Mitochondrial trifunctional protein deficiency. The disease is caused by mutations affecting the gene represented in this entry.

Function

[ECHA_HUMAN] Bifunctional subunit.

5zrv, resolution 7.70Å

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OCA