5m7d

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Blood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with glycerolBlood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with glycerol

Structural highlights

5m7d is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:ABO (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

See Also

5m7d, resolution 1.20Å

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