Structural highlights5koe is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Ligands: | , , , , , , , |
| Activity: | Galactoside 2-alpha-L-fucosyltransferase, with EC number 2.4.1.69 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function[FUT1_ARATH] Involved in cell wall biosynthesis. Is both necessary and sufficient for the addition of the terminal fucosyl residue on xyloglucan side chains, but is not involved in the fucosylation of other cell wall components (PubMed:10373113, PubMed:11743104, PubMed:11854459, PubMed:14730072). Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066).[1] [2] [3] [4] [5]
References
- ↑ Perrin RM, DeRocher AE, Bar-Peled M, Zeng W, Norambuena L, Orellana A, Raikhel NV, Keegstra K. Xyloglucan fucosyltransferase, an enzyme involved in plant cell wall biosynthesis. Science. 1999 Jun 18;284(5422):1976-9. PMID:10373113
- ↑ Sarria R, Wagner TA, O'Neill MA, Faik A, Wilkerson CG, Keegstra K, Raikhel NV. Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1. Plant Physiol. 2001 Dec;127(4):1595-606. PMID:11743104
- ↑ Vanzin GF, Madson M, Carpita NC, Raikhel NV, Keegstra K, Reiter WD. The mur2 mutant of Arabidopsis thaliana lacks fucosylated xyloglucan because of a lesion in fucosyltransferase AtFUT1. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3340-5. Epub 2002 Feb 19. PMID:11854459 doi:http://dx.doi.org/10.1073/pnas.052450699
- ↑ Pena MJ, Ryden P, Madson M, Smith AC, Carpita NC. The galactose residues of xyloglucan are essential to maintain mechanical strength of the primary cell walls in Arabidopsis during growth. Plant Physiol. 2004 Jan;134(1):443-51. PMID:14730072 doi:http://dx.doi.org/10.1104/pp.103.027508
- ↑ Chou YH, Pogorelko G, Young ZT, Zabotina OA. Protein-protein interactions among xyloglucan-synthesizing enzymes and formation of Golgi-localized multiprotein complexes. Plant Cell Physiol. 2015 Feb;56(2):255-67. doi: 10.1093/pcp/pcu161. Epub 2014 Nov, 11. PMID:25392066 doi:http://dx.doi.org/10.1093/pcp/pcu161
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