5d1q
IsdB NEAT2 bound by clone D2-06IsdB NEAT2 bound by clone D2-06
Structural highlights
Function[ISDB_STAAB] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). |
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