5l4t

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Crystal structure of FimH lectin domain in complex with 2-Deoxy-HeptylmannosideCrystal structure of FimH lectin domain in complex with 2-Deoxy-Heptylmannoside

Structural highlights

5l4t is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:fimH, b4320, JW4283 (ECOLI), fimH (ECOLI)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.

5l4t, resolution 1.90Å

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