Crystal structure of a complex between bovine chymotrypsin and ecotinCrystal structure of a complex between bovine chymotrypsin and ecotin

Structural highlights

1n8o is a 4 chain structure with sequence from Bovin and Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Chymotrypsin, with EC number 3.4.21.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ECOT_ECOLI] General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The strength of inhibition does not appear to be correlated with a particular protease specificity.[HAMAP-Rule:MF_00706]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1n8o, resolution 2.00Å

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OCA