2n7b
NMR structure of human I-type lectin domain-glycan complexNMR structure of human I-type lectin domain-glycan complex
Structural highlights
Function[SIGL8_HUMAN] Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
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