4x8k

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Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2

Structural highlights

4x8k is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[SIGA_MYCTO] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.[HAMAP-Rule:MF_00963] [RBPA_MYCTO] Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.

4x8k, resolution 2.20Å

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OCA