4ez8

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Crystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolateCrystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate

Structural highlights

4ez8 is a 1 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:Tyms (LK3 transgenic mice)
Activity:Thymidylate synthase, with EC number 2.1.1.45
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).

See Also

4ez8, resolution 1.17Å

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