Solution structure of MAST205-PDZ complexed with the C-terminus of a rabies virus G proteinSolution structure of MAST205-PDZ complexed with the C-terminus of a rabies virus G protein

Structural highlights

2kqf is a 2 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:MAST205 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[MAST2_HUMAN] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592]

See Also

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OCA