4m2x

Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ)Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ)

Structural highlights 4m2x is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , , Activity: Dihydrofolate reductase, with EC number 1.5.1.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [DYR_MYCTU] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also Dihydrofolate reductase

spinqualitylabelsall models 4m2x, resolution 2.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image