Crystal structure of PIP4KIIBETA T201M complex with AMPCrystal structure of PIP4KIIBETA T201M complex with AMP

Structural highlights

3x05 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:1-phosphatidylinositol-5-phosphate 4-kinase, with EC number 2.7.1.149
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[PI42B_HUMAN] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.[1]

References

  1. Castellino AM, Parker GJ, Boronenkov IV, Anderson RA, Chao MV. A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J Biol Chem. 1997 Feb 28;272(9):5861-70. PMID:9038203

3x05, resolution 2.50Å

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