Crystal Structure of Mtb ThyA in complex with dUMP and RaltitrexedCrystal Structure of Mtb ThyA in complex with dUMP and Raltitrexed

Structural highlights

4fox is a 8 chain structure with sequence from Myctu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:MT2834, MTV002.29c, Rv2764c, thyA (MYCTU)
Activity:Thymidylate synthase, with EC number 2.1.1.45
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TYSY_MYCTU] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).

See Also

4fox, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA