Putative Phosphatase Ynic from Escherichia coli K12Putative Phosphatase Ynic from Escherichia coli K12
Structural highlights
1te2 is a 2 chain structure with sequence from Escherichia coli o157:h7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
[YNIC_ECOLI] Catalyzes strongly the dephosphorylation of 2-deoxyglucose 6-phosphate (2dGlu6P) and slightly the dephosphorylation of mannose 6-phosphate (Man6P), 2-deoxyribose-5-phosphate (2dRib5P), ribose-5-phosphate (Rib5P) and glucose-6-phosphate (Glu6P).[1][2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Kuznetsova E, Proudfoot M, Sanders SA, Reinking J, Savchenko A, Arrowsmith CH, Edwards AM, Yakunin AF. Enzyme genomics: Application of general enzymatic screens to discover new enzymes. FEMS Microbiol Rev. 2005 Apr;29(2):263-79. PMID:15808744 doi:S0168-6445(05)00004-5
↑Kuznetsova E, Proudfoot M, Gonzalez CF, Brown G, Omelchenko MV, Borozan I, Carmel L, Wolf YI, Mori H, Savchenko AV, Arrowsmith CH, Koonin EV, Edwards AM, Yakunin AF. Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. J Biol Chem. 2006 Nov 24;281(47):36149-61. Epub 2006 Sep 21. PMID:16990279 doi:10.1074/jbc.M605449200
