Opioid receptor

<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry 4djh)' scene=>

Opioid receptor (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them.

• The μ-opioid receptor binds morphine. For more details on μ-opioid receptor see Mu Opioid Receptor Bound to a Morphinan Antagonist.
  
• The κ-opioid receptor binds opium-type ligands.
  
• The δ-opioid receptor binds enkephalins.

3D structures of opioid receptor3D structures of opioid receptor

Updated on 02-December-2014

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• δ-opioid receptor
  • 4ej4 – mOpR + naltrindole - mouse
    
• κ-opioid receptor
  • 4djh – hOpR + opioid antagonist - human
    
• Nociceptin/orphanin FQ opioid receptor
  • 4ea3 – hOpR + peptide mimetic
    
• μ-opioid receptor
  • 4dkl – mOpR + opioid antagonist