3sgi

Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosisCrystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis

Structural highlights 3sgi is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Related: 1zau Gene: lig, ligA, MT3094, MTV012.28c, Rv3014c (Mycobacterium tuberculosis) Activity: DNA ligase (NAD(+)), with EC number 6.5.1.2 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DNLJ_MYCTU] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] See Also DNA ligase

spinqualitylabelsall models 3sgi, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image