3pvo

Monoclinic form of Human C-Reactive ProteinMonoclinic form of Human C-Reactive Protein

Structural highlights

3pvo is a 20 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Related:	3pvn, 1lj7
Gene:	CRP, PTX1 (Homo sapiens)
Resources:	FirstGlance, OCA, RCSB, PDBsum

Function

[CRP_HUMAN] Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

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OCA