4nlg

Y-family DNA polymerase chimera Dbh-Dpo4(243-245)-DbhY-family DNA polymerase chimera Dbh-Dpo4(243-245)-Dbh

FunctionFunction

[DPO4_SULAC] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity).

About this StructureAbout this Structure

4nlg is a 3 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Mukherjee P, Wilson RC, Lahiri I, Pata JD. Three Residues of the Interdomain Linker Determine the Conformation and Single-Base Deletion Fidelity of Y-family Translesion Polymerases. J Biol Chem. 2014 Jan 10. PMID:24415763 doi:http://dx.doi.org/10.1074/jbc.M113.537860

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OCA

[1] Mukherjee P, Wilson RC, Lahiri I, Pata JD. Three Residues of the Interdomain Linker Determine the Conformation and Single-Base Deletion Fidelity of Y-family Translesion Polymerases. J Biol Chem. 2014 Jan 10. PMID:24415763 doi:http://dx.doi.org/10.1074/jbc.M113.537860

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