4hog

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Template:STRUCTURE 4hog

Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H)Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H)

Template:ABSTRACT PUBMED 24568657

About this StructureAbout this Structure

4hog is a 2 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J Med Chem. 2014 Mar 6. PMID:24568657 doi:http://dx.doi.org/10.1021/jm401916j

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