4kg8
Crystal structure of light mutantCrystal structure of light mutant
FunctionFunction
[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
About this StructureAbout this Structure
4kg8 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Almo, S C.
- Bonanno, J B.
- IFN, Atoms-to-Animals:.The Immune Function Network.
- Kumar, P R.
- Liu, W.
- NYSGRC, New York Structural Genomics Research Consortium.
- Nathenson, S G.
- Zhan, C.
- Atoms-to-animals: the immune function network
- Bind tnf receptor hvem and ltbr
- Cytokine
- Dcr3
- Hvem
- Ifn
- Immunity
- Jelly-roll fold
- Ltbr
- Membrane
- N-glycosylation
- New york structural genomics research consortium
- Nysgrc
- Protein structure initiative
- Psi-biology
- Secreted protein
- Structural genomic
- Tnf superfamily