Opioid receptor

<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry 4djh)' scene=>

Opioid receptor (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them.

• The μ-opioid receptor binds morphine. For more details on μ-opioid receptor see Mu Opioid Receptor Bound to a Morphinan Antagonist.
  
• The κ-opioid receptor binds opium-type ligands.
  
• The δ-opioid receptor binds enkephalins.

3D structures of opioid receptor3D structures of opioid receptor

Updated on 19-August-2014

δ-opioid receptorδ-opioid receptor

4ej4 – mOpR + naltrindole - mouse

κ-opioid receptorκ-opioid receptor

4djh – hOpR + opioid antagonist - human

Nociceptin/orphanin FQ opioid receptorNociceptin/orphanin FQ opioid receptor

4ea3 – hOpR + peptide mimetic

μ-opioid receptor'μ-opioid receptor'

4dkl – mOpR + opioid antagonist