4jvs

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Template:STRUCTURE 4jvs

Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3

Template:ABSTRACT PUBMED 23588383

FunctionFunction

[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.

About this StructureAbout this Structure

4jvs is a 2 chain structure with sequence from Homo sapiens and Legionella drancourtii llap12. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Yu Q, Hu L, Yao Q, Zhu Y, Dong N, Wang DC, Shao F. Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP. Cell Res. 2013 Apr 16. doi: 10.1038/cr.2013.54. PMID:23588383 doi:10.1038/cr.2013.54

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