4i6y
3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate
FunctionFunction
[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
About this StructureAbout this Structure
4i6y is a 2 chain structure with sequence from Pseudomonas mevalonii. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g