3zfe

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Template:STRUCTURE 3zfe

Human enterovirus 71 in complex with capsid binding inhibitor WIN51711Human enterovirus 71 in complex with capsid binding inhibitor WIN51711

Template:ABSTRACT PUBMED 23509286

FunctionFunction

[A9X4C2_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]

About this StructureAbout this Structure

3zfe is a 4 chain structure with sequence from Human enterovirus 71. Full crystallographic information is available from OCA.

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