3t6b

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Template:STRUCTURE 3t6b

Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 AngstromsStructure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms

Template:ABSTRACT PUBMED 22493238

FunctionFunction

[DPP3_HUMAN] Cleaves Arg-Arg-beta-naphthylamide.

About this StructureAbout this Structure

3t6b is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Bezerra GA, Dobrovetsky E, Viertlmayr R, Dong A, Binter A, Abramic M, Macheroux P, Dhe-Paganon S, Gruber K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6525-30. Epub 2012 Apr 9. PMID:22493238 doi:10.1073/pnas.1118005109

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