1usx
Crystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialosideCrystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialoside
Template:ABSTRACT PUBMED 15016893
FunctionFunction
[HN_NDVB] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity).
About this StructureAbout this Structure
1usx is a 3 chain structure with sequence from Avian paramyxovirus type 1. Full crystallographic information is available from OCA.