4f3c
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-ACrystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A
FunctionFunction
[E8NLP5_SALET] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]
About this StructureAbout this Structure
4f3c is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50. Full crystallographic information is available from OCA.
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OCACategories:
- Adenosylhomocysteine nucleosidase
- Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50
- Almo, S C.
- Bonanno, J B.
- Haapalainen, A M.
- Schramm, V L.
- Thomas, K.
- 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase
- Acting on glycosyl bond
- Adenosylhomocysteine nucleosidase activity
- Hydrolase-hydrolase inhibitor complex
- L-methionine biosynthetic process from s-adenosylmethionine
- L-methionine salvage from methylthioadenosine
- Methylthioadenosine nucleosidase activity