Template:STRUCTURE 4j4d

Structure of P51G Cyanovirin-N swapped dimer in the P21212 space groupStructure of P51G Cyanovirin-N swapped dimer in the P21212 space group

FunctionFunction

[CVN_NOSEL] Mannose-binding lectin.[1] [2]

About this StructureAbout this Structure

4j4d is a 4 chain structure with sequence from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

ReferenceReference

  1. Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30. PMID:9210678
  2. Botos I, Wlodawer A. Cyanovirin-N: a sugar-binding antiviral protein with a new twist. Cell Mol Life Sci. 2003 Feb;60(2):277-87. PMID:12678493

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OCA