4f50
Y-family DNA polymerase chimera Dbh-Dbh-Dpo4Y-family DNA polymerase chimera Dbh-Dbh-Dpo4
Template:ABSTRACT PUBMED 23245850
FunctionFunction
[DPO4_SULAC] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity).
About this StructureAbout this Structure
4f50 is a 3 chain structure with sequence from Sulso. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Wilson RC, Jackson MA, Pata JD. Y-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion Specificity. Structure. 2012 Dec 11. pii: S0969-2126(12)00420-0. doi:, 10.1016/j.str.2012.11.005. PMID:23245850 doi:http://dx.doi.org/10.1016/j.str.2012.11.005