2qnn
HIV-1 protease in complex with a multiple decorated pyrrolidine-based inhibitorHIV-1 protease in complex with a multiple decorated pyrrolidine-based inhibitor
About this StructureAbout this Structure
2qnn is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s