2dxs
Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitorCrystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor
About this StructureAbout this Structure
2dxs is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ikegashira K, Oka T, Hirashima S, Noji S, Yamanaka H, Hara Y, Adachi T, Tsuruha J, Doi S, Hase Y, Noguchi T, Ando I, Ogura N, Ikeda S, Hashimoto H. Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors. J Med Chem. 2006 Nov 30;49(24):6950-3. PMID:17125247 doi:10.1021/jm0610245