2yoh

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Template:STRUCTURE 2yoh

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitorPlasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor

Template:ABSTRACT PUBMED 23240776

About this StructureAbout this Structure

2yoh is a 2 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Cui H, Carrero-Lerida J, Silva AP, Whittingham JL, Brannigan JA, Ruiz-Perez LM, Read KD, Wilson KS, Gonzalez-Pacanowska D, Gilbert IH. Synthesis and evaluation of alpha-thymidine analogues as novel antimalarials. J Med Chem. 2012 Dec 27;55(24):10948-57. doi: 10.1021/jm301328h. Epub 2012 Dec, 14. PMID:23240776 doi:10.1021/jm301328h

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