3vl3

3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 340 MPa3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 340 MPa

FunctionFunction

[LEU3_SHEON] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.

About this StructureAbout this Structure

3vl3 is a 1 chain structure with sequence from Sheon. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Nagae T, Kawamura T, Chavas LM, Niwa K, Hasegawa M, Kato C, Watanabe N. High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):300-9. Epub 2012 Feb 14. PMID:22349232 doi:http://dx.doi.org/10.1107/S0907444912001862

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OCA

[1] Nagae T, Kawamura T, Chavas LM, Niwa K, Hasegawa M, Kato C, Watanabe N. High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):300-9. Epub 2012 Feb 14. PMID:22349232 doi:http://dx.doi.org/10.1107/S0907444912001862

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