RNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURESRNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURES

Structural highlights

1ns1 is a 2 chain structure with sequence from Influenza a virus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:J02169 (Influenza A virus)
Resources:FirstGlance, OCA, RCSB, PDBsum

Publication Abstract from PubMed

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.

A novel RNA-binding motif in influenza A virus non-structural protein 1.,Chien CY, Tejero R, Huang Y, Zimmerman DE, Rios CB, Krug RM, Montelione GT Nat Struct Biol. 1997 Nov;4(11):891-5. PMID:9360601[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Chien CY, Tejero R, Huang Y, Zimmerman DE, Rios CB, Krug RM, Montelione GT. A novel RNA-binding motif in influenza A virus non-structural protein 1. Nat Struct Biol. 1997 Nov;4(11):891-5. PMID:9360601
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