3u4h
CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose templateCD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template
Template:ABSTRACT PUBMED 23840430
FunctionFunction
[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
About this StructureAbout this Structure
3u4h is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Moreau C, Liu Q, Graeff R, Wagner GK, Thomas MP, Swarbrick JM, Shuto S, Lee HC, Hao Q, Potter BV. CD38 Structure-Based Inhibitor Design Using the 1-Cyclic Inosine 5'-Diphosphate Ribose Template. PLoS One. 2013 Jun 19;8(6):e66247. Print 2013. PMID:23840430 doi:10.1371/journal.pone.0066247