1gen
| |||||||
| , resolution 2.15Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , and | ||||||
| Gene: | HUMAN GELATINASE A (Homo sapiens) | ||||||
| Activity: | Gelatinase A, with EC number 3.4.24.24 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
C-TERMINAL DOMAIN OF GELATINASE A
OverviewOverview
The crystal structure of the haemopexin-like C-terminal domain of gelatinase A reveals that it is a four-bladed beta-propeller protein. The four blades are arranged around a channel-like opening in which Ca2+ and a Na-Cl+ ion pair are bound.
DiseaseDisease
Known diseases associated with this structure: Osteolysis, idiopathic, Saudi type OMIM:[120360], Winchester syndrome OMIM:[120360]
About this StructureAbout this Structure
1GEN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of the haemopexin-like C-terminal domain of gelatinase A., Libson AM, Gittis AG, Collier IE, Marmer BL, Goldberg GI, Lattman EE, Nat Struct Biol. 1995 Nov;2(11):938-42. PMID:7583664
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