2wd7

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Template:STRUCTURE 2wd7

File:2wd7.png

PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750

Template:ABSTRACT PUBMED 19527033

About this StructureAbout this Structure

2wd7 is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R. One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J Med Chem. 2009 Jun 15. PMID:19527033 doi:10.1021/jm900414x

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