Proteopedia

4agm

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Template:STRUCTURE 4agm

File:4agm.jpg

Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086

Template:ABSTRACT PUBMED 17015838

About this StructureAbout this Structure

4agm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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