3tow

Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I ComplexCrystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex

FunctionFunction

[MB12B_HUMAN] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.

About this StructureAbout this Structure

3tow is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Boura E, Hurley JH. Structural basis for membrane targeting by the MVB12-associated beta-prism domain of the human ESCRT-I MVB12 subunit. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1901-6. Epub 2012 Jan 9. PMID:22232651 doi:http://dx.doi.org/10.1073/pnas.1117597109

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OCA

[1] Boura E, Hurley JH. Structural basis for membrane targeting by the MVB12-associated beta-prism domain of the human ESCRT-I MVB12 subunit. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1901-6. Epub 2012 Jan 9. PMID:22232651 doi:http://dx.doi.org/10.1073/pnas.1117597109

[xtra 1]