Template:STRUCTURE 3vi8

File:3vi8.jpg

Human PPRR alpha ligand binding domain in complex with a synthetic agonist APHM13Human PPRR alpha ligand binding domain in complex with a synthetic agonist APHM13

Template:ABSTRACT PUBMED 22185225

About this StructureAbout this Structure

3vi8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Kuwabara N, Oyama T, Tomioka D, Ohashi M, Yanagisawa J, Shimizu T, Miyachi H. Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype. J Med Chem. 2012 Jan 26;55(2):893-902. Epub 2012 Jan 10. PMID:22185225 doi:10.1021/jm2014293

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OCA