3ig6
Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complexLow molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Template:ABSTRACT PUBMED 19703768
About this StructureAbout this Structure
3ig6 is a 4 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ West CW, Adler M, Arnaiz D, Chen D, Chu K, Gualtieri G, Ho E, Huwe C, Light D, Phillips G, Pulk R, Sukovich D, Whitlow M, Yuan S, Bryant J. Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5712-5. Epub 2009 Aug 7. PMID:19703768 doi:10.1016/j.bmcl.2009.08.008
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OCACategories:
- Pages with broken file links
- Homo sapiens
- U-plasminogen activator
- Adler, M.
- Whitlow, M.
- Blood coagulation
- Disulfide bond
- Egf-like domain
- Fibrinolysis
- Glycoprotein
- Hydrolase
- Kringle
- Phosphoprotein
- Plasminogen activation
- Protease
- S1 site inhibitor
- Secreted
- Selective
- Serine protease
- Structure-based drug design
- Urokinase
- Zymogen