3axh
Crystal structure of isomaltase in complex with isomaltoseCrystal structure of isomaltase in complex with isomaltose
Template:ABSTRACT PUBMED 21925939
FunctionFunction
[MALX3_YEAST] Major isomaltase (alpha-1,6-glucosidase) required for isomaltose utilization. Preferentially hydrolyzes isomaltose, palatinose, and methyl-alpha-glucoside, with little activity towards isomaltotriose or longer oligosaccharides. Does not hydrolyze maltose.[1] [2]
About this StructureAbout this Structure
3axh is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Yamamoto K, Miyake H, Kusunoki M, Osaki S. Steric hindrance by 2 amino acid residues determines the substrate specificity of isomaltase from Saccharomyces cerevisiae. J Biosci Bioeng. 2011 Sep 16. PMID:21925939 doi:10.1016/j.jbiosc.2011.08.016
- ↑ Yamamoto K, Nakayama A, Yamamoto Y, Tabata S. Val216 decides the substrate specificity of alpha-glucosidase in Saccharomyces cerevisiae. Eur J Biochem. 2004 Aug;271(16):3414-20. PMID:15291818 doi:10.1111/j.1432-1033.2004.04276.x
- ↑ Teste MA, Francois JM, Parrou JL. Characterization of a new multigene family encoding isomaltases in the yeast Saccharomyces cerevisiae, the IMA family. J Biol Chem. 2010 Aug 27;285(35):26815-24. doi: 10.1074/jbc.M110.145946. Epub, 2010 Jun 18. PMID:20562106 doi:10.1074/jbc.M110.145946