3t5z
Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamideCrystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide
Template:ABSTRACT PUBMED 21952494
About this StructureAbout this Structure
3t5z is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Di Fiore A, Maresca A, Alterio V, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem Commun (Camb). 2011 Nov 14;47(42):11636-8. Epub 2011 Sep 26. PMID:21952494 doi:10.1039/c1cc14575d
- ↑ Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406
- ↑ Scott AD, Phillips C, Alex A, Flocco M, Bent A, Randall A, O'Brien R, Damian L, Jones LH. Thermodynamic optimisation in drug discovery: a case study using carbonic anhydrase inhibitors. ChemMedChem. 2009 Dec;4(12):1985-9. PMID:19882701 doi:10.1002/cmdc.200900386